adrenal cortex ( cortex of adrenal gland) the outer, firm layer comprising the larger part of the adrenal gland it secretes mineralocorticoids, androgens, and glucocorticoids. Both norepinephrine and epinephrine are part of the 'fight-or-flight' response of the sympathetic nervous system. cor´tices) ( L.) the outer layer of an organ or other structure, as distinguished from its inner substance or medulla. These hormones travel via the bloodstream and act on various other body tissues. The chromaffin cells of the adrenal medulla also releases norepinephrine, which affects the amygdala, and impacts attention and responses. The adrenal glands secrete different hormones which act as chemical messengers. Within it are chromaffin cells, which release epinephrine, which takes part in regulating metabolism, heart rate, vasodilation and vasoconstriction. The adrenal medulla is at the center of the adrenal gland, and is connected to the sympathetic division of the autonomic nervous system. For females, the zona reticularis is the only source of male sex hormones, while males can also produce them in the testicles. The adrenal cortex is also a secondary source of male sex hormones, as the innermost layer, the zona reticularis, produces DHEA and androstenedione, which are sources of conversion to DHA and testosterone.

The middle layer, the zona fasciculata, produces and secretes glucocorticoids, including cortisol, which is involved in glucose metabolism and the stress response mechanism. The outermost layer, the zona glomerulosa, releases aldosterone, which increases water and salt retention in the kidneys. The cortex has three layers, the zona glomerulosa, zona fasciculata, and zona reticularis. The adrenal cortex produces several hormones.

The adrenal cortex runs along the outer edge of the adrenal gland and is the primary section involved in stress response. The adrenal glands are endocrine glands that sit on top of the kidneys and take part in the stress response pathway, secondary production of androgens, and blood osmoregulation.

Cortical sex hormones adrenal gland